Gas chromatography/mass spectrometric identification of dopaminergic metabolites in striata of rats treated with L-DOPA
| Autor: | H. Legros, Catherine Lange, Jean Costentin, Corinne Loutelier-Bourhis, J.-J. Bonnet |
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| Rok vydání: | 2004 |
| Předmět: |
Male
Trimethylsilyl Dopamine Agents Mass spectrometry Gas Chromatography-Mass Spectrometry Analytical Chemistry Antiparkinson Agents Levodopa Rats Sprague-Dawley Benserazide chemistry.chemical_compound medicine Animals Spectroscopy Chromatography Chemistry Organic Chemistry Dopaminergic Mass spectrometric Corpus Striatum Rats Sprague dawley Drug Therapy Combination Gas chromatography Injections Intraperitoneal Ex vivo medicine.drug |
| Zdroj: | Rapid Communications in Mass Spectrometry. 18:571-576 |
| ISSN: | 1097-0231 0951-4198 |
| DOI: | 10.1002/rcm.1369 |
| Popis: | The ex vivo identification of dopaminergic metabolites present in rat striata after (L-DOPA + benserazide) treatment is reported. The different metabolites have been identified as the trimethylsilyl derivatives in the striatal extracts by gas chromatography/mass spectrometry. |
| Databáze: | OpenAIRE |
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