Validation of an Argentine version of Lupus Quality of Life questionnaire

Autor: A Sanchez, G Gomez, E Lucero, M S Yacuzzi, J Sarano, L. Gonzalez Lucero, G Betancur, M. Machado Escobar, R N Martinez, Alejandro Martínez, L. M. Galindo, J.C. Barreira, F Dal Pra, M M Mayer, M C Orozco, Verónica Bellomio, Mirta Santana, V. Juarez, María Victoria Collado
Rok vydání: 2016
Předmět:
Zdroj: Lupus. 25:1615-1622
ISSN: 1477-0962
0961-2033
DOI: 10.1177/0961203316660202
Popis: Objective To determine reproducibility and validity of an Argentine version of the Lupus Quality of Life questionnaire (LupusQoL) and to determine cut-off values in the questionnaire. Materials and methods One hundred and forty-seven systemic lupus erythematosus patients (American College of Rheumatology 1982/1997) were assessed from April 2014 to July 2014. Demographic and socioeconomic variables were collected, as well as SELENA/SLEDAI, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index Score, comorbidities and treatment data. Patients completed LupusQoL-Argentine version and European Quality of Life Questionnaire (EuroQoL-5D). Internal consistency and reliability were examined. Convergent validity with EuroQoL-5D was assessed through analysis of latent classes, which established homogeneous categories from the responses of each domain of LupusQoL and for the total. Results Out of 147 patients, 93.2% were female, mean age 36.4 ± 11.1 years, mean disease duration 2.7 ± 9 years, mean SELENA/SLEDAI 2.7 ± 3 points. The cut-off point that defined good or bad quality of life was 0.739 for EuroQoL 5D and 63 for LupusQoL. Cut-off values for each LupusQoL domain were also defined, creating two classes in each of them. There was moderate to high concordance to classify quality of life (Kappa = 0.74, 95% confidence interval = 0.54, 0.95). Conclusion The Argentine version of LupusQoL is a valid, reliable and reproducible instrument to assess quality of life. In this study, cut-off points that allow the classification of patients regarding whether they have good or bad quality of life are established for the first time.
Databáze: OpenAIRE
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