Safety and Outcome of Endovascular Treatment for Minor Ischemic Stroke: Results From the Multicenter Clinical Registry of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands
| Autor: | Goldhoorn, R.B., Mulder, M.J.H.L., Jansen, I.G.H., Zwam, W.H. van, Staals, J., Lugt, A. van der, Dippel, D.W.J., Lingsma, H.F., Vos, J.A., Boiten, J., Wijngaard, I.R. van den, Majoie, C.B.L.M., Roos, Y.B.W.E.M., Oostenbrugge, R.J. van, Goldhoorn, R.J.B., Schonewille, W.J., Coutinho, J.M., Wermer, M.J.H., Walderveen, M.A.A. van, Hofmeijer, J., Martens, J.M., Nijeholt, G.J.L.A., Roozenbeek, B., Emmer, B.J., Bruijn, S.F. de, Dijk, L.C. van, Worp, H.B. van der, R.H. lo, Dijk, E.J. van, Boogaarts, H.D., Kort, P.L.M. de, Peluso, J.J.P., Berg, J.S.P. van den, Hasselt, B.A.A.M. van, Aerden, L.A.M., Dallinga, R.J., Uyttenboogaart, M., Eshghi, O., Schreuder, T.H.C.M.L., Heijboer, R.J.J., Keizer, K., Yo, L.S.F., Hertog, H.M. den, Sturm, E.J.C., Sprengers, M.E.S., Jenniskens, S.F.M., Berg, R. van den, Yoo, A.J., Beenen, L.F.M., Roosendaal, S.D., Kallen, B.F.W. van der, Es, A. van, Emmer, B., Bot, J., Doormaal, P.J. van, Postma, A., Flach, H.Z., Ghannouti, N. el, Sterrenberg, M., Puppels, C., Pellikaan, W., Sprengers, R., Elfrink, M., Meris, J. de, Vermeulen, T., Geerlings, A., Vemde, G. van, Simons, T., Rijswijk, C. van, Messchendorp, G., Bongenaar, H., Bodde, K., Kleijn, S., Lodico, J., Droste, H., Wollaert, M., Jeurrissen, D., Bos, E., Drabbe, Y., Zweedijk, B., Khalilzada, M., Venema, E., Chalos, V., Compagne, K.J., Geuskens, R.R., Straaten, T. van, Ergezen, S., Harmsma, R.R.M., Muijres, D., Jong, A. de, Hinsenveld, W., Berkhemer, O.A., Boers, A.M.M., Huguet, J., Groot, P.F.C., Mens, M.A., Kranendonk, K.R. van, Treurniet, K.M., Kappelhof, M., Tolhuijsen, M.L., Alves, H., MR CLEAN Registry Investigators |
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| Přispěvatelé: | Neurology, Radiology & Nuclear Medicine, Public Health, Klinische Neurowetenschappen, RS: Carim - B05 Cerebral small vessel disease, RS: CARIM - R3.03 - Cerebral small vessel disease, MUMC+: MA Niet Med Staf Neurologie (9), Promovendi CD, RS: Carim - B06 Imaging, Beeldvorming, MUMC+: DA BV Medisch Specialisten Radiologie (9), RS: CARIM - R3.11 - Imaging, MUMC+: MA Med Staf Spec Neurologie (9), MUMC+: MA Neurologie (3), MUMC+: DA BV AIOS Nucleaire Geneeskunde (9), RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: DA BV AIOS Radiologie (9), Amsterdam Neuroscience - Neurovascular Disorders, ACS - Atherosclerosis & ischemic syndromes, ACS - Microcirculation, Radiology and Nuclear Medicine, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Radiology and nuclear medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
endovascular treatment Time Factors Severity of Illness Index THERAPY ANGIOGRAPHY law.invention Brain Ischemia Disability Evaluation 0302 clinical medicine Randomized controlled trial Modified Rankin Scale law Risk Factors Occlusion Prospective Studies Registries Stroke Netherlands Ischemic stroke medicine.diagnostic_test LARGE VESSEL OCCLUSION Rehabilitation Endovascular Procedures minor symptoms Middle Aged THROMBECTOMY Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3] Treatment Outcome Cerebrovascular Circulation Cardiology ANTERIOR CIRCULATION Female TRIAL SCALE SCORE Cardiology and Cardiovascular Medicine Intracranial Hemorrhages medicine.medical_specialty Clinical Decision-Making 03 medical and health sciences large vessel oclusion All institutes and research themes of the Radboud University Medical Center Internal medicine medicine Humans Artery occlusion cardiovascular diseases Aged business.industry Patient Selection Other Research Radboud Institute for Health Sciences [Radboudumc 0] Recovery of Function MILD medicine.disease Arterial occlusion Angiography Surgery Observational study Neurology (clinical) business 030217 neurology & neurosurgery INTRAARTERIAL TREATMENT |
| Zdroj: | Journal of Stroke and Cerebrovascular Diseases, 28(3), 542-549. W.B. Saunders Journal of Stroke & Cerebrovascular Diseases, 28(3), 542-549. Elsevier Journal of Stroke and Cerebrovascular Diseases, 28, 542-549 Journal of Stroke and Cerebrovascular Diseases, 28, 3, pp. 542-549 Journal of stroke and cerebrovascular diseases, 28(3), 542-549. W.B. Saunders Ltd Journal of Stroke & Cerebrovascular Diseases, 28(3), 542-549. ELSEVIER SCIENCE BV Goldhoorn, R B, Mulder, M J H L, Jansen, I G H, van Zwam, W H, Staals, J, van der Lugt, A, Dippel, D W J, Lingsma, H F, Vos, J A, Boiten, J, van den Wijngaard, I R, Majoie, C B L M, Roos, Y B W E M, van Oostenbrugge, R J & MR CLEAN Registry investigators. 2019, ' Safety and Outcome of Endovascular Treatment for Minor Ischemic Stroke: Results From the Multicenter Clinical Registry of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands ', Journal of Stroke and Cerebrovascular Diseases, vol. 28, no. 3, pp. 542-549 . https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.10.029 Journal of Stroke and Cerebrovascular Diseases, 28(3), 542-549. W.B. Saunders Ltd Journal of Stroke and Cerebrovascular Diseases, 28(3), 542-549 |
| ISSN: | 1052-3057 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2018.10.029 |
| Popis: | Goal: Insufficient data is available about safety and efficacy of endovascular treatment (EVT) in patients with minor stroke symptoms because these patients were excluded from most randomized trials. We aimed to compare characteristics, functional outcome, and complications in patients with minor ischemic stroke National Institutes of Health Stroke Scale score ≤5 (NIHSS score ≤5) and moderate to severe ischemic stroke (NIHSS score ≥6) due to intracranial proximal artery occlusion of the anterior circulation who underwent EVT. Materials and Methods: We report patients with an anterior circulation occlusion who were included between March 2014 and June 2016 in the multicenter randomized clinical trial of EVT of acute ischemic stroke in the Netherlands Registry, a prospective, multicenter, observational study for stroke centers that perform EVT in the Netherlands. Minor ischemic stroke was defined as baseline NIHSS score of 5 or less. Primary outcome is the modified Rankin Scale (mRS) score at 90 days. Secondary outcomes include symptomatic intracranial hemorrhage (sICH) and mortality. Findings: Seventy-one (5.5%) patients had a NIHSS score of 5 or less. Functional independence (mRS 0-2 at 90 days) was reached in 75% of these patients, compared to 40% of patients with NIHSS score of 6 or more. sICH occurred in 4% of patients, of which 1% occurred peri-interventionally. Death occurred in 6% of patients. Conclusions: Patients with minor ischemic stroke with an intracranial proximal arterial occlusion of the anterior circulation who underwent EVT have a high chance of favorable outcome and appear to have low occurrence of treatment-related sICH. Therefore, our results encourage the use of EVT for minor ischemic stroke in the absence of effect estimates from controlled studies. |
| Databáze: | OpenAIRE |
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