Novel Synthesis of Core-Shell Biomaterials from Polymeric Filaments with a Bioceramic Coating for Biomedical Applications
| Autor: | Aura-Cătălina Mocanu, Catalina-Andreea Dascalu, Florin Miculescu, Stefan Ioan Voicu, Lucian Toma Ciocan, Andreea Elena Constantinescu, Tudor Mihai Butte, Andreea Madalina Pandele, Robert-Cătălin Ciocoiu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Biocompatibility bioceramic coating Nanotechnology 02 engineering and technology Bioceramic engineering.material 010402 general chemistry 01 natural sciences Thermoplastic polyurethane chemistry.chemical_compound Coating Tissue engineering Polylactic acid Materials Chemistry core-shell structure Ceramic chemistry.chemical_classification biogenic hydroxyapatite fused deposition modelling Surfaces and Interfaces Polymer 021001 nanoscience & nanotechnology 0104 chemical sciences Surfaces Coatings and Films chemistry lcsh:TA1-2040 visual_art engineering visual_art.visual_art_medium fused filament fabrication 0210 nano-technology lcsh:Engineering (General). Civil engineering (General) |
| Zdroj: | Coatings, Vol 10, Iss 3, p 283 (2020) Coatings Volume 10 Issue 3 |
| ISSN: | 2079-6412 |
| Popis: | Bone tissue engineering is constantly in need of new material development with improved biocompatibility or mechanical features closer to those of natural bone. Other important factors are the sustainability, cost, and origin of the natural precursors involved in the technological process. This study focused on two widely used polymers in tissue engineering, namely polylactic acid (PLA) and thermoplastic polyurethane (TPU), as well as bovine-bone-derived hydroxyapatite (HA) for the manufacturing of core-shell structures. In order to embed the ceramic particles on the polymeric filaments surface, the materials were introduced in an electrical oven at various temperatures and exposure times and under various pressing forces. The obtained core-shell structures were characterized in terms of morphology and composition, and a pull-out test was used to demonstrate the particles adhesion on the polymeric filaments structure. Thermal properties (modulated temperature and exposure time) and the pressing force&rsquo s influence upon HA particles&rsquo insertion degree were evaluated. More to the point, the form variation factor and the mass variation led to the optimal technological parameters for the synthesis of core-shell materials for prospect additive manufacturing and regenerative medicine applications. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|