Scleroderma Renal Crisis in a Case of Mixed Connective Tissue Disease Treated Successfully with Angiotensin-Converting Enzyme Inhibitors

Autor:	Iman Khamayseh, Jomana Madieh, Alaa Hrizat, Abdurrahman Hamadah, Kamel A Gharaibeh
Rok vydání:	2021
Předmět:	medicine.medical_specialty Scleroderma Renal Crisis 030232 urology & nephrology Case Report Gastroenterology Polymyositis Scleroderma 03 medical and health sciences 0302 clinical medicine Mixed connective tissue disease Internal medicine medicine skin and connective tissue diseases 030203 arthritis & rheumatology biology business.industry Angiotensin-converting enzyme Dermatomyositis medicine.disease Diseases of the genitourinary system. Urology Nephrology biology.protein RC870-923 Complication business Proto-oncogene tyrosine-protein kinase Src
Zdroj:	Case Reports in Nephrology, Vol 2021 (2021) Case Reports in Nephrology
ISSN:	2090-665X 2090-6641
Popis:	Mixed connective tissue disease (MCTD) is a rheumatic disease syndrome with overlapping features of scleroderma, systemic lupus erythematosus, and polymyositis. An extremely rare but serious complication that can occur in MCTD is scleroderma renal crisis (SRC). There have been different approaches to the treatment of SRC associated with MCTD. We present a case of MCTD with chronic features of Raynaud’s phenomenon, dermatomyositis, and thrombocytopenia complicated with acute SRC which showed a great response to ACE inhibitors. Here, we advise the early and aggressive use of ACE inhibitors as soon as SRC is suspected.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623d80f0f13bf46b269b729e24e6eba0 https://doi.org/10.1155/2021/8862405 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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