Scleroderma Renal Crisis in a Case of Mixed Connective Tissue Disease Treated Successfully with Angiotensin-Converting Enzyme Inhibitors
Autor: | Iman Khamayseh, Jomana Madieh, Alaa Hrizat, Abdurrahman Hamadah, Kamel A Gharaibeh |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Scleroderma Renal Crisis 030232 urology & nephrology Case Report Gastroenterology Polymyositis Scleroderma 03 medical and health sciences 0302 clinical medicine Mixed connective tissue disease Internal medicine medicine skin and connective tissue diseases 030203 arthritis & rheumatology biology business.industry Angiotensin-converting enzyme Dermatomyositis medicine.disease Diseases of the genitourinary system. Urology Nephrology biology.protein RC870-923 Complication business Proto-oncogene tyrosine-protein kinase Src |
Zdroj: | Case Reports in Nephrology, Vol 2021 (2021) Case Reports in Nephrology |
ISSN: | 2090-665X 2090-6641 |
Popis: | Mixed connective tissue disease (MCTD) is a rheumatic disease syndrome with overlapping features of scleroderma, systemic lupus erythematosus, and polymyositis. An extremely rare but serious complication that can occur in MCTD is scleroderma renal crisis (SRC). There have been different approaches to the treatment of SRC associated with MCTD. We present a case of MCTD with chronic features of Raynaud’s phenomenon, dermatomyositis, and thrombocytopenia complicated with acute SRC which showed a great response to ACE inhibitors. Here, we advise the early and aggressive use of ACE inhibitors as soon as SRC is suspected. |
Databáze: | OpenAIRE |
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