Complete Radiologic Response in an Anaplastic Oligodendroglioma Treated with Temozolomide and Bevacizumab
| Autor: | Gustavo Dos Santos Fernandes, Artur Katz, Yana Augusta Sakis Novis, Aknar Calabrich |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Radiologic Response
medicine.medical_specialty Chemotherapy Temozolomide Bevacizumab business.industry Published online: March 2009 medicine.medical_treatment Tumor resection Lymphoblastic lymphoma Anaplastic oligodendroglioma lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease lcsh:RC254-282 Surgery Radiation therapy Brain neoplasms Targeted therapies Oncology medicine business medicine.drug |
| Zdroj: | Case Reports in Oncology Case Reports in Oncology, Vol 2, Iss 1, Pp 57-60 (2009) |
| ISSN: | 1662-6575 |
| Popis: | In this case report, we describe a rare case of a 32-year-old man who presented a highly aggressive, fast growing anaplastic oligodendroglioma five years after being treated with whole brain radiotherapy for a CNS recurrence of a lymphoblastic lymphoma. Initially, the patient was submitted to a surgical intervention and partial tumor resection, which allowed us to establish the pathologic diagnosis and the presence of a 1p deletion. Shortly after the operation the tumor grew back, exerting important mass effect. Since no radiation therapy or surgery could be used and the patient faced a critical condition, chemotherapy was started with a combination of temozolomide and bevacizumab. Immediately after the first cycle a marked clinical and radiological improvement was documented. |
| Databáze: | OpenAIRE |
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