Popis: |
Background and Setting: The article reviews a rare case of a 9-year-old female patient with a swelling in the anterior maxillary region, associated with the missing left lateral incisor. Her radiograph revealed an impacted, left lateral incisor that was surrounded by a well-defined radiolucency with corticated margins, on the distal aspect of the crown and root. Numerous hypotheses for the pathogenesis of AOT have been proposed over the years, but controversy still exists, as to the precise odontogenic source of origin. Through this review, we have extensively discussed the differential hypothesis regarding this enigmatic tumor. The Adenomatoid odontogenic tumor (AOT) is a rare (0.6 to 38.5% of odontogenic tumors) benign tumor of epithelial origin that predominantly occurs in children and young adults (88% occurs in 2nd and 3rd decades of life). The tumor is found twice as frequent in females, as in males. Two forms of the tumors are identified: intraosseous and extraosseous. Seventy-one percent of cases were of the follicular type, with the impacted maxillary (64.3%) canine (60%), being predominantly affected. Expert morphological diagnosis is required to establish a differential diagnosis, especially from ameloblastoma, in order to prevent an extensive surgery. The term Adenomatoid odontogenic tumor, a century old, benign tumor of odontogenic origin, was first proposed by Philipsen and Birn, which was later accepted by WHO in 1971. 1AOT may constitute about 2.2% to 7.1% of odontogenic tumors, as reported in a recent study. The differential diagnosis of AOT is crucial in terms of surgical management, and local excision is the treatment of choice for AOT. The increasing number of reports on AOT points to the fact that the tumor develops more frequently than formerly expected. 1The tumor has been called as the 2/3rds tumor, as 2/3rd cases appear in females, 2/3rd cases in the maxilla, and 2/3rd cases appear in relation to impacted teeth. [2] The AOT can be subtyped based on its clinical and radiological findings. The follicular or intraosseous type and extrafollicular or extraosseous types; of which the follicular type is more common and it is localized around the crown of a retained tooth which also include the upper part of the tooth root. [1]There are three well-established clinical variants of AOT namely the extraosseous [3] or peripheral (2.3%), and intraosseous: [3] pericoronal (70.8%) and extracoronal (26.9%). Multifocal AOT described by Larsson et al. was included in the bracket of multiple Adenomatoid odontogenic hamartomas |