Long-term High Salt Diet Causes Hypertension and Decreases Renal Expression of Vascular Endothelial Growth Factor in Sprague-Dawley Rats
| Autor: | Jian-Wei Gu, Emily Young, Amelia Purser Bailey, Wei Tan, Megan Shparago |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Mean arterial pressure
medicine.medical_specialty Proteinuria business.industry Salt diet Article Vascular endothelial growth factor chemistry.chemical_compound Blood pressure Endocrinology chemistry Renal injury Internal medicine Internal Medicine Albuminuria Medicine Northern blot medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of the American Society of Hypertension : JASH. 2(4) |
| ISSN: | 1933-1711 |
| Popis: | We seek to determine: 1) whether a long-term high salt diet induces hypertension and renal injury in Sprague-Dawley (SD) rats and 2) whether the high salt diet-induced hypertension and renal injury are associated with decreased renal VEGF expression. Twelve 10-wk-old male SD rats received a high salt diet (HS, 8%) and twelve SD rats received a normal salt diet (NS, 0.5 %) for 8 weeks. Using a tail cuff, weekly monitoring showed that blood pressure increased significantly after 6, 7, & 8 wks in HS group, compared to NS group (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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