Production and removal of superoxide anion radical by artificial metalloenzymes and redox-active metals

Autor: Kenichiro Tanaka, François Bouteau, Takashi Kadono, Takuya Hiramatsu, Hiroka Furukawa, Tadashi Okobira, Kazuya Uezu, Licca Tanaka, Tomonori Kawano, Tomoko Kagenishi, Ken Yokawa, Stefano Mancuso, František Baluška, Cun Lin, Reina Inokuchi, Junichiro Iwase
Rok vydání: 2014
Předmět:
Zdroj: Communicative & Integrative Biology
ISSN: 1942-0889
Popis: Generation of reactive oxygen species is useful for various medical, engineering and agricultural purposes. These include clinical modulation of immunological mechanism, enhanced degradation of organic compounds released to the environments, removal of microorganisms for the hygienic purpose, and agricultural pest control; both directly acting against pathogenic microorganisms and indirectly via stimulation of plant defense mechanism represented by systemic acquired resistance and hypersensitive response. By aiming to develop a novel classes of artificial redox-active biocatalysts involved in production and/or removal of superoxide anion radicals, recent attempts for understanding and modification of natural catalytic proteins and functional DNA sequences of mammalian and plant origins are covered in this review article.
Databáze: OpenAIRE