Childhood psychopathology retrospectively assessed among adults with early onset major depression
| Autor: | Anne Maddocks, Maurizio Fava, Jonathan E. Alpert, Jerrold F. Rosenbaum |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Imipramine Adolescent Child Behavior Disorders Comorbidity Double-Blind Method Recurrence Fluoxetine Sertraline mental disorders medicine Humans Psychiatry Major depressive episode Child Depression (differential diagnoses) Retrospective Studies Depressive Disorder Bulimia nervosa Mental Disorders Middle Aged medicine.disease Anxiety Disorders Substance abuse Psychiatry and Mental health Clinical Psychology Paroxetine 1-Naphthylamine Personality Development Phobic Disorders Anxiety Major depressive disorder Female Age of onset medicine.symptom Psychology Selective Serotonin Reuptake Inhibitors |
| Zdroj: | Journal of affective disorders. 31(3) |
| ISSN: | 0165-0327 |
| Popis: | Prevalence and impact of comorbidity in early onset major depressive disorder were studied in 116 depressed adult outpatients whose onset of first major depressive episode occurred by age 18. Eighty-eight percent of these patients had at least one additional comorbid Axis I lifetime diagnosis including: social phobia (28%), simple phobia (16%), alcohol (17%) and cannabis (13%) abuse/dependence, and bulimia nervosa (8%). Comorbid anxiety disorders preceded the onset of major depression in two-thirds of individuals while comorbid substance abuse/dependence followed the onset of major depression in two-thirds and predicted more frequent occurrences into adulthood. In contrast to frequency of episodes, severity and duration of an index episode of major depression were not influenced by comorbidity. |
| Databáze: | OpenAIRE |
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