The Glomerular Filtration Rate (GFR) at Dialysis Initiation and Mortality in Chronic Kidney Disease (CKD) in East Asian Populations: A Meta-analysis
| Autor: | Xiang-Zhen Zeng, Jun Ai, Xin Lin |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Risk medicine.medical_specialty China medicine.medical_treatment 030232 urology & nephrology Renal function Subgroup analysis chronic kidney disease (CKD) 03 medical and health sciences 0302 clinical medicine Asian People Japan Renal Dialysis Internal medicine Internal Medicine medicine Humans 030212 general & internal medicine Renal Insufficiency Chronic Dialysis Aged Proportional Hazards Models Korea late dialysis initiation early dialysis initiation business.industry Proportional hazards model Mortality rate Hazard ratio General Medicine Middle Aged medicine.disease mortality Disease Progression Fluid Therapy Female Original Article business glomerular filtration rate (GFR) Cohort study Kidney disease Glomerular Filtration Rate |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 |
| Popis: | Objective The impact of dialysis initiation on survival is still somewhat controversial. Given that race or ethnicity has been observed to be a predictor of mortality and the rate of progression of chronic kidney disease, we conducted a meta-analysis to investigate the effect of early vs. late dialysis initiation on mortality in East Asian populations. Methods All eligible cohort studies of target were selected from the MEDLINE (PubMed), EMBASE, The Cochrane Library and the Clinical Trials Registry databases from inception to October 2014. The data were extracted with all-cause mortality rates as the primary outcome, and pooled adjusted hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated. Results Ten studies examined the association between early vs. late dialysis initiation and mortality. Compared to late dialysis initiation, patients who received early dialysis initiation had a higher overall mortality risk (adjusted HR, 1.36; 95% CI, 1.0-1.85; p |
| Databáze: | OpenAIRE |
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