Obesity, dynapenia, and their combination: Implications for bone mineral density in Brazilian adults—the Pró-Saúde study
| Autor: | Eduardo Faerstein, Flávia F. Bezerra, Vivian Wahrlich, Amina Chain |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Civil servants Fat mass 03 medical and health sciences 0302 clinical medicine Bone Density Internal medicine medicine Humans Obesity Aged Aged 80 and over Bone mineral 030109 nutrition & dietetics Nutrition and Dietetics Hand Strength Dual energy business.industry Middle Aged medicine.disease Cross-Sectional Studies Cohort Female business Brazil Bone mass |
| Zdroj: | Nutrition. 81:110898 |
| ISSN: | 0899-9007 |
| Popis: | This study aimed to evaluate bone mineral density (BMD) in the presence or absence of dynapenia or obesity in Brazilian adults.This is a cross-sectional study conducted in 502 adults (age: 33-81 y; 51% women) participating in the Pró-Saúde study, a cohort of civil servants at the university campuses in Rio de Janeiro, Brazil. Body composition and BMD were determined by dual energy x-ray absorptiometry. Handgrip strength was measured using a dynamometer. According to measures of handgrip strength (≤19 kg for women; ≤32 kg for men) and fat mass (30% for men;40% for women), participants were classified into four groups: non-obese non-dynapenic, obese non-dynapenic, non-obese dynapenic, and obese dynapenic. The association between BMD at each specific bone site and obesity, dynapenia, and their interaction was evaluated using a general linear model.The prevalence of dynapenic obesity was 14% in men and 15.2% in women. Dynapenia alone was not associated with BMD at any site in either men nor women. Obesity and dynapenia interacted to influence BMD in women (P0.05). Total body, lumbar spine, and femoral neck BMD were higher by 6.3%, 9.3%, and 10.4%, respectively, in dynapenic obese women compared with their non-obese counterparts (P0.05). In men, obesity, dynapenia, and their combination were not associated with BMD at any site.Our results suggest that dynapenia, obesity, and their combination may affect BMD in a sex-dependent manner. In the presence of dynapenia, fat mass appears to exert a protective effect on BMD in women, but not in men. |
| Databáze: | OpenAIRE |
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