A Prospective, observational, Italian multi-center registry of self-aPposing® cOronary Stents in patients presenting with ST-segment Elevation Myocardial InfarcTION: The iPOSITION registry
| Autor: | Giuseppe Andò, Nicola Maddestra, Juan Luis Gutiérrez-Chico, Marco Contarini, Francesco Saporito, Serena Rossi, Giuseppe De Iaco, Marco Zimarino, Rosario Parisi, Federico Archilletti, Sabina Gallina, Livio Giuliani, Giorgio Sacchetta |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Target lesion
medicine.medical_specialty medicine.medical_treatment nitinol stent Myocardial Infarction primary PCI acute myocardial infarction interventional device Balloon acute myocardial infarction ST-segment elevation myocardial infarction clinical trials self-apposing stent nitinol stent interventional device/innovation percutaneous coronary intervention (PCI) complex primary PCI drug-eluting stent Percutaneous Coronary Intervention Internal medicine medicine Clinical endpoint self-apposing stent drug-eluting stent ST segment Humans Myocardial infarction cardiovascular diseases Prospective Studies Registries interventional device/innovation clinical trials business.industry Percutaneous coronary intervention Stent Drug-Eluting Stents Thrombosis General Medicine medicine.disease Interventional Cardiology innovation Death ST-segment elevation myocardial infarction surgical procedures operative Treatment Outcome Drug-eluting stent Cardiology ST Elevation Myocardial Infarction Stents Original Article percutaneous coronary intervention (PCI) Cardiology and Cardiovascular Medicine business complex |
| Zdroj: | Cardiology Journal |
| Popis: | Background: Primary percutaneous coronary intervention (pPCI) in ST-segment elevation myocardial infarction (STEMI) can be challenging for high thrombus burden and catecholamine-induced vasoconstriction. The Xposition-S stent was designed to prevent stent undersizing and minimize strut malapposition. We evaluated 1-year clinical outcomes of a nitinol, self-apposing ® , sirolimus-eluting stent, pre-mounted on a novel balloon delivery system, in de novo lesions of patients presenting with STEMI undergoing pPCI. Methods: The iPOSITION is a prospective, multicenter, post-market, observational study. The primary endpoint, target lesion failure (TLF), was defined as the composite of cardiac death (CD), recurrent target vessel myocardial infarction (TV-MI), and clinically driven target lesion revascularization (TLR). Results: The study enrolled 247 STEMI patients from 7 Italian centers. Both device and procedural success occurred in 99.2% of patients, without any death, TV-MI, TLR, or stent thrombosis (ST) during the hospital stay and at 30-day follow-up. At 1 year, TLF occurred in 2.6%, CD occurred in 1.7%, TV-MI occurred in 0.4%, and TLR in 0.4% of patients. The 1-year ST rate was 0.4%. Conclusions: The use of an X-position S self-apposing ® stent is feasible in STEMI pPCI, with excellent post-procedural results and 1-year outcomes. |
| Databáze: | OpenAIRE |
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