Exploration of New Contrasts, Targets, and MR Imaging and Spectroscopy Techniques for Neuromuscular Disease – A Workshop Report of Working Group 3 of the Biomedicine and Molecular Biosciences COST Action BM1304 MYO-MRI
| Autor: | Ralph, Sinkus, Strijkers, Gustav, Araujo, Ericky C.A., Azzabou, Noura, Bendahan, David, Blamire, Andrew, Burakiewicz, Jedrek, Carlier, Pierre, Damon, Bruce, Deligianni, Xeni, Froeling, Martijn, Heerschap, Arend, Hollingsworth, Kieren, Hooijmans, Melissa, Karampinos, Dimitrios, Loudos, George, Madelin, Guillaume, Marty, Benjamin, Nagel, Armin, Nederveen, Aart, Nelissen, Jules, Santini, Francesco, Scheidegger, Olivier, Schick, Fritz, Sinclair, Christopher, Sinkus, Ralph, de Sousa, Paulo, Straub, Volker, Walter, Glenn, Kan, Hermien |
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| Přispěvatelé: | Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute of Myology, Nuclear Magnetic Resonance Laboratory, Centre de résonance magnétique biologique et médicale (CRMBM), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS), Newcastle University [Newcastle], Laboratoire Spécification et Vérification [Cachan] (LSV), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), University Medical Center [Utrecht], Department of Radiology, Radboud University Medical Center [Nijmegen], Technol Educ Inst Athens, Centre de résonance magnétique des systèmes biologiques (CRMSB), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Service MIRCEN (MIRCEN), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), University Hospital Erlangen = Uniklinikum Erlangen, Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC), University of Amsterdam [Amsterdam] (UvA), Università degli studi di Genova = University of Genoa (UniGe), EAWAG, Dept. Surface Waters Res. & Management, Swiss Federal Insitute of Aquatic Science and Technology [Dübendorf] (EAWAG), Physique des ondes pour la médecine, Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de synthèse organique (DCSO), École polytechnique (X)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Department of Neurology, ACS - Atherosclerosis & ischemic syndromes, Amsterdam Neuroscience - Brain Imaging, Biomedical Engineering and Physics, AMS - Restoration & Development, ACS - Diabetes & metabolism, Radiology and Nuclear Medicine, ACS - Heart failure & arrhythmias, Institut de Myologie, Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Association française contre les myopathies (AFM-Téléthon)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Pierre et Marie Curie - Paris 6 (UPMC), Résonance magnétique des systèmes biologiques (RMSB), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, University-Hospital Erlangen, University of Erlangen-Nuremberg, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Dipartimento di Matematica e Informatica [Perugia] (DMI), Università degli Studi di Perugia (UNIPG), Swiss Federal Institute for Environmental Science and Technology [Dübendorf] (EAWAG), Université Paris Diderot - Paris 7 (UPD7)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 (UPD7)-Université Paris 13 (UP13)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB), Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), University of Genoa (UNIGE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Magnetic Resonance Spectroscopy Neurology muscle [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging [SDV]Life Sciences [q-bio] Contrast Media Review Magnetic Resonance Imaging/methods 0302 clinical medicine Cost action Dog Diseases ComputingMilieux_MISCELLANEOUS media_common Magnetic Resonance Spectroscopy/methods medicine.diagnostic_test Muscles Outcome measures Neuromuscular Diseases Neuromuscular disease Magnetic Resonance Imaging 3. Good health Neuromuscular Diseases/diagnostic imaging biomarker [SDV.IB]Life Sciences [q-bio]/Bioengineering MRI MRS medicine.medical_specialty Clinical Neurology 03 medical and health sciences Dogs Muscles/diagnostic imaging Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15] medicine media_common.cataloged_instance Animals Humans Medical physics European Union European union Biomedicine Dog Diseases/diagnostic imaging outcome measure business.industry Magnetic resonance imaging medicine.disease Clinical trial 030104 developmental biology myo-mri Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neuromuscular Diseases Journal of Neuromuscular Diseases, 2019, 6 (1), pp.1-30. ⟨10.3233/JND-180333⟩ Journal of neuromuscular diseases, 6(1), 1-30. IOS Press Journal of Neuromuscular Diseases, IOS Press, 2019, 6 (1), pp.1-30. ⟨10.3233/JND-180333⟩ Journal of Neuromuscular Diseases, 6(1), 1. IOS Press Journal of Neuromuscular Diseases, 6, 1-30 Journal of Neuromuscular Diseases, 6, 1, pp. 1-30 |
| ISSN: | 2214-3599 2214-3602 |
| DOI: | 10.3233/JND-180333⟩ |
| Popis: | Contains fulltext : 203339.pdf (Publisher’s version ) (Open Access) Neuromuscular diseases are characterized by progressive muscle degeneration and muscle weakness resulting in functional disabilities. While each of these diseases is individually rare, they are common as a group, and a large majority lacks effective treatment with fully market approved drugs. Magnetic resonance imaging and spectroscopy techniques (MRI and MRS) are showing increasing promise as an outcome measure in clinical trials for these diseases. In 2013, the European Union funded the COST (co-operation in science and technology) action BM1304 called MYO-MRI (www.myo-mri.eu), with the overall aim to advance novel MRI and MRS techniques for both diagnosis and quantitative monitoring of neuromuscular diseases through sharing of expertise and data, joint development of protocols, opportunities for young researchers and creation of an online atlas of muscle MRI and MRS. In this report, the topics that were discussed in the framework of working group 3, which had the objective to: Explore new contrasts, new targets and new imaging techniques for NMD are described. The report is written by the scientists who attended the meetings and presented their data. An overview is given on the different contrasts that MRI can generate and their application, clinical needs and desired readouts, and emerging methods. |
| Databáze: | OpenAIRE |
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