Determination of N-(2-benzoyloxyethyl)-norfenfluramine (JP 992) and its metabolites in urine
Autor: | A. H. Beckett, E. V. B. Shenoy, L. G. Brookes |
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Rok vydání: | 1971 |
Předmět: | |
Zdroj: | The Journal of pharmacy and pharmacology. 23(12) |
ISSN: | 0022-3573 |
Popis: | A gas-liquid chromatographic method of determination of norfenfluramine and N-2-hydroxyethylnorfenfluramine is described. Also a method is reported to determine N-(2-benzoyloxyethyl)norfenfluramine and its metabolites containing the m-trifluoromethyl- benzyl and -benzoyl moieties in urine, by oxidation of these to m-trifluoromethyl benzoic acid followed by methylation and gas-liquid chromatography. |
Databáze: | OpenAIRE |
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