Determination of N-(2-benzoyloxyethyl)-norfenfluramine (JP 992) and its metabolites in urine

Autor:	A. H. Beckett, E. V. B. Shenoy, L. G. Brookes
Rok vydání:	1971
Předmět:	Pharmacology Chromatography Chromatography Gas organic chemicals Pharmaceutical Science Urine Methylation chemistry.chemical_compound chemistry Norfenfluramine Fenfluramine Methods Organic chemistry Humans Oxidation-Reduction Benzoic acid
Zdroj:	The Journal of pharmacy and pharmacology. 23(12)
ISSN:	0022-3573
Popis:	A gas-liquid chromatographic method of determination of norfenfluramine and N-2-hydroxyethylnorfenfluramine is described. Also a method is reported to determine N-(2-benzoyloxyethyl)norfenfluramine and its metabolites containing the m-trifluoromethyl- benzyl and -benzoyl moieties in urine, by oxidation of these to m-trifluoromethyl benzoic acid followed by methylation and gas-liquid chromatography.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fa52203590e5538da8886c218ac35f https://pubmed.ncbi.nlm.nih.gov/4402022 Zobrazit plný text záznamu Plný text