Mild Cobalt(III)-Catalyzed Allylative C−F/C−H Functionalizations at Room Temperature

Autor:	Lutz Ackermann, Daniel Zell, Valentin Müller, Stefan Grimme, Markus Bursch, Uttam Dhawa, Rubén Rubio Presa
Rok vydání:	2017
Předmět:	Reaction conditions Reaction mechanism 010405 organic chemistry Chemistry Organic Chemistry Substrate (chemistry) chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences Cobalt catalyst Polymer chemistry Organic chemistry Cobalt
Zdroj:	Chemistry - A European Journal. 23:12145-12148
ISSN:	0947-6539
DOI:	10.1002/chem.201702528
Popis:	Cobalt-catalyzed C−F/C−H functionalizations were achieved under exceedingly mild reaction conditions. Thus, a sustainable cobalt catalyst enabled synthetically meaningful C−H activations with ample substrate scope at ambient temperature of 25 °C, thereby delivering perfluoroallylated (hetero)arenes. Detailed experimental and computational mechanistic studies on the C−F/C−H functionalizations provided strong support for a facile C−F cleavage.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f9fa1588cc1ba53555636e45a534e3 https://doi.org/10.1002/chem.201702528 Zobrazit plný text záznamu Plný text ve formátu PDF