Inversion of the hemispheric laterality of the anterior cingulate gyrus in schizophrenics
| Autor: | Elba B Tornese, Eduardo F. Albanese, Alicia Merlo, Tomás Mascitti, Elena Gómez, Alfonso M. Albanese, Víctor Konopka |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male medicine.medical_specialty Psychosis Central nervous system Audiology Gyrus Cinguli Functional Laterality Anterior cingulate gyrus Female patient Limbic System medicine Humans Right hemisphere Biological Psychiatry Aged Neuropsychology Brain Middle Aged medicine.disease medicine.anatomical_structure Residual schizophrenia Laterality Schizophrenia Female Autopsy Psychology Neuroscience |
| Zdroj: | Biological Psychiatry. 38:13-21 |
| ISSN: | 0006-3223 |
| DOI: | 10.1016/0006-3223(94)00257-4 |
| Popis: | The anterior cingulate gyrus (acg) is involved in mechanisms of attention and emotion, where the right hemisphere is considered to be dominant. One of the models for neuropsychological dysfunction in schizophrenia suggests an impairment in the balance of lateralized functions. Fourteen adult human female brains, having no macroscopic lesions, were used in this study. Seven brains came from female patients with clinical diagnoses of residual schizophrenia (DSM-111-R; APA 1987). Seven female brains were used as controls. Thirteen male brains were also studied, with the sole purpose of establishing the typicality of the female controls. All schizophrenic brains were age matched with control brains. Right laterality for weight (71.4%) and surface (85.7%) was observed in the acg of female control brains. The inversion of this laterality in a significant number of the schizophrenic cases was the most relevant finding in this study. |
| Databáze: | OpenAIRE |
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