Psychodynamic-oriented psychological assessment predicts evolution to schizophrenia at 8-year follow-up in adolescents hospitalized for a manic/mixed episode: interest of an overall subjective rating
| Autor: | Nicole Duplant, David Cohen, Raffaella Lucanto, Caroline Thompson, Fanny Gollier-Briant, Claudine Laurent, Angèle Consoli, Marie-José Bailly-Salin, Annie Lemoigne, Estelle Louët, Nicolas Bodeau, Julie Brunelle, Charlotte Mayer, Michèle Martin |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Bipolar Disorder Adolescent Intraclass correlation behavioral disciplines and activities Psychoanalysis Rorschach test Young Adult Predictive Value of Tests Physiology (medical) mental disorders medicine Humans Psychological testing Bipolar disorder Psychiatry Retrospective Studies Psychiatric Status Rating Scales Framingham Risk Score General Neuroscience medicine.disease Schizophrenia Clinical Global Impression Female Schizophrenic Psychology Psychology Psychosocial Clinical psychology Follow-Up Studies |
| Zdroj: | Journal of physiology, Paris. 104(5) |
| ISSN: | 1769-7115 |
| Popis: | Little is known concerning the prognostic significance of manic/mixed episodes in adolescents. In particular, whether the use of psychodynamic-oriented projective psychological testing predicts evolution to schizophrenia at follow-up has not been established. Eighty subjects, aged 12–20 years old, consecutively hospitalized for a manic or mixed episode between 1994 and 2003 were recruited. All patients were contacted in 2005–2006 for a follow-up assessment. For the subgroup of adolescents (N = 40) who had psychodynamic-oriented psychological testing (Rorschach and TAT), two scores regarding psychosocial risk and schizophrenia risk were computed using the clinical global impression (CGI) assessment based on an overall subjective rating given by a panel of expert psychologists who reviewed all protocols. At follow-up (average 8 years), 25 (62.5%) patients, 16 females and nine males, were assessed: 14 still had a diagnosis of bipolar disorder; eight changed to schizo-affective disorder and three to schizophrenia. Inter-rater reliability of both CGI-risk scores (psychosocial risk and schizophrenia risk) showed good clinical consensus with intraclass correlation and Kappa scores ranging from 0.53 to 0.75. Univariate analysis showed that CGI-psychosocial risk score (p = 0.017), type of index episode (p = 0.049) and CGI-schizophrenia risk score (p = 0.09) were associated with transition to schizophrenia spectrum disorder at follow-up. Age, sex, socioeconomic status, duration of stay and the presence of psychotic features at index episode were not associated with the transition. We conclude that the CGI assessment appears to be valid to score risk of poor outcome using psychodynamic-oriented psychological testing and that these scores may predict, in part, the transition to schizophrenia in adolescents with a history of manic/mixed episode. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect