Bile reflux in gastric ulcer: the effect of smoking, metoclopramide and carbenoxolone sodium
| Autor: | J. E. Dippy, John Rhodes, S. Cross |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Adult
Male medicine.medical_specialty Metoclopramide Carbenoxolone sodium Anti-Inflammatory Agents Carbenoxolone Gastroenterology Bile reflux Internal medicine Glycyrrhiza medicine Bile Humans Stomach Ulcer Aged Meal Plants Medicinal biology business.industry Stomach Smoking digestive oral and skin physiology Reflux Succinates General Medicine Middle Aged medicine.disease biology.organism_classification Triterpenes digestive system diseases medicine.anatomical_structure Female business medicine.drug |
| Zdroj: | Current Medical Research and Opinion. 1:569-575 |
| ISSN: | 1473-4877 0300-7995 |
| DOI: | 10.1185/03007997309111723 |
| Popis: | SummaryThe degree of bile reflux into the stomach was examined during a standard test meal in 26 patients with gastric ulcer. The test meal was repeated within 7 days in 10 patients who smoked during the second test; the degree of reflux increased considerably in six. In a further 10 patients the test was repeated 15 minutes after an oral dose of metoclopramide; there was no change in the degree of reflux. In 6 other patients the effect of a single dose and also of one week's treatment with carbenoxolone was examined. There was no change in the degree of bile reflux observed in either the second or third tests.Although oral metoclopramide and carbenoxolone appeared to have no effect on bile reflux into the stomach, smoking increased reflux considerably in 6 of 10 patients. The significance of these findings is discussed with reference to therapy in gastric ulcer. |
| Databáze: | OpenAIRE |
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