The Impact of Stage and Molecular Subtypes on Survival Outcomes in Young Women with Breast Cancer
| Autor: | T Subramanyeshwar Rao, CK Naidu, K. V. V. N. Raju, Nisha Hariharan, Aparna Suryadevara, Santa Ayyagari, Sudha S Murthy, M V T Krishnamohan, Naren Boleneni, Senthil Rajappa |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Oncology
medicine.medical_specialty business.industry Breast Neoplasms Middle Aged Prognosis medicine.disease Survival Analysis Young age Treatment Outcome Breast cancer Internal medicine Pediatrics Perinatology and Child Health Cohort medicine Humans Female Young adult Stage (cooking) Presentation (obstetrics) business Neoplasm Staging Retrospective Studies |
| Zdroj: | Journal of Adolescent and Young Adult Oncology. 8:628-634 |
| ISSN: | 2156-535X 2156-5333 |
| DOI: | 10.1089/jayao.2019.0023 |
| Popis: | Young women form a unique cohort in breast cancer, with evidence suggesting a later stage at presentation with more aggressive cancers. We aimed at evaluating the prognostic significance of young age and the impact of stage and molecular subtypes on survival. We conducted an audit of a prospectively maintained database at our institute between 2010 and 2014. All women with available receptor status and documented follow-up were included. The young breast cancer (YBC) cohort comprised 103 women and 230 women constituted the comparator arm (45-55 years). The median follow-up was 4 years. The YBC had a higher incidence of hormone negative tumors (61.1% vs. 46.3% |
| Databáze: | OpenAIRE |
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