A case of myelodysplastic syndrome with abnormal megakaryocytes and ins(8;3)(q24;q21q26)
| Autor: | J. Reynaud, J. Jaubert, Vasselon C, C.P. Brizard, M. Bachy-Delhomme, P. Calmard, M.F. Bertheas |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
Cancer Research Pathology medicine.medical_specialty Chromosome Disorders Biology Megakaryocyte Bone Marrow Genetics medicine Humans Thrombopoiesis Molecular Biology Cells Cultured Chromosome Aberrations Cytogenetics Karyotype Middle Aged medicine.disease Chromosome Banding medicine.anatomical_structure Male patient Karyotyping Myelodysplastic Syndromes Immunology Chromosome abnormality Bone marrow Chromosomes Human Pair 3 Refractory anemia with excess of blasts Megakaryocytes Chromosomes Human Pair 8 |
| Zdroj: | Cancer genetics and cytogenetics. 55(1) |
| ISSN: | 0165-4608 |
| Popis: | We report a 56-year-old male patient with refractory anemia with excess of blasts in transformation (RAEB-T) who had an ins(8;3)(q24;q21q26) as the sole chromosome abnormality in bone marrow (BM) cells. The findings of disturbed thrombocytopoiesis with numerous micromegakaryocytes suggest that it could be a variant of the classic ins(3;3)(q26;q21q26) described in hematologic malignancies with abnormal thrombopoiesis. |
| Databáze: | OpenAIRE |
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