Chemotherapy advances in locally advanced head and neck cancer
| Autor: | Nadir Ahmad, Peter Georges, Kumar Rajagopalan, Chady Abboud leon, Kamyar Nader, Priya Singh, Gregory J. Kubicek |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Oncology
medicine.medical_specialty Pathology medicine.medical_treatment Locally advanced Targeted therapy stomatognathic system Internal medicine medicine otorhinolaryngologic diseases Epidermal growth factor receptor Topic Highlight Head and neck neoplasms Cisplatin Chemotherapy biology business.industry Head and neck cancer Induction chemotherapy medicine.disease stomatognathic diseases biology.protein business medicine.drug |
| Zdroj: | World journal of clinical oncology. 5(5) |
| ISSN: | 2218-4333 |
| Popis: | The management of locally advanced unresectable head and neck squamous cell cancer (HNSCC) continues to improve. One of the major advances in the treatment of HNSCC was the addition of chemotherapy to radiation in the treatment of non-surgical patients. The majority of the data regarding chemotherapy in HNSCC involve cisplatin chemotherapy with concurrent radiation. However, several new approaches have included targeted therapy against epidermal growth factor receptor and several recent studies have explored the role of induction chemotherapy in the treatment of HNSCC. The purpose of this article is to provide an overview of the role of chemotherapy in the treatment of locally advanced HNSCC. |
| Databáze: | OpenAIRE |
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