Isolation of Diphenyl-Substituted Tetronic Acids from Cultures of Paxillus Atrotomentosus
| Autor: | L.R. Brady, M.C. Gaylord, G.M. Hatfield, R.G. Benedict |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Electrophoresis
Chromatography Chromatography Paper Infrared Rays Ultraviolet Rays Silica gel Basidiomycota Spectrum Analysis Pharmaceutical Science Infrared spectroscopy Ether Pigments Biological Mass spectrometry Solvent Pigment chemistry.chemical_compound chemistry visual_art Methods visual_art.visual_art_medium Organic chemistry Furans Tetronic acid Mycelium |
| Zdroj: | Journal of Pharmaceutical Sciences. 59:1420-1423 |
| ISSN: | 0022-3549 |
| DOI: | 10.1002/jps.2600591010 |
| Popis: | Pigments which accumulated in surface cultures of Paxillus atrotomentosus (Batsch) Fr. were studied. The nutrient broth and mycelium of 2-month-old cultures were blended, and the pigments were partitioned into ether. Two pigments were isolated by dry-column chromatogrphy using a silica gel adsorbent and ether saturated with concentrated HCl as a chromatographic solvent. The major pigment was identified as xerocomic acid, and the minor pigment was shown to be atromentic acid. Identification of these acids was based on UV and IR spectra, mass spectral fragmentation patterns, high-resolution mass spectroscopy, and properties of their acetyl derivatives. Examination of fresh carpophores of P. atrotomentosus failed to demonstrate detectable amounts of either of these tetronic acids. These pigments have been reported to occur in fresh carpophores of some species in the Boletaceae and Gomphidiaceae, but this is the first reported presence of any diphenyl-substituted tetronic acid in the saprophytic culture of a fungus. |
| Databáze: | OpenAIRE |
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