Whole-body inflammation in trauma patients. An autopsy study
| Autor: | Karel Kubat, Hans K. S. Nuytinck, Xavier J. M. W. Offermans, R. Jan A. Goris |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Time Factors Adolescent Neutrophils Multiple Organ Failure Inflammation Autopsy Severity of Illness Index Pathogenesis Leukocyte Count Severity of illness Medicine Animals Humans Shock Traumatic Child Aged Retrospective Studies Aged 80 and over Respiratory Distress Syndrome Respiratory distress business.industry Respiratory disease Infant Organ Size Hypoxia (medical) Middle Aged medicine.disease Surgery Brain Injuries Child Preschool Wounds and Injuries Female Rabbits medicine.symptom business |
| Zdroj: | Archives of surgery (Chicago, Ill. : 1960). 123(12) |
| ISSN: | 0004-0010 1519-1524 |
| Popis: | • In a review of autopsy specimens and reports in 35 trauma cases, we found signs of generalized inflammation and tissue damage with increases in organ weights in organs not primarily injured. These abnormalities occurred independent of the time of death and were also found in patients who died of brain injury alone. The most pronounced signs of inflammation and increases in organ weights were found when the adult respiratory distress syndrome, hypovolemic shock, or multiple organ failure were the causes of death. These findings are similar to those found in several organs of rabbits after four hours of complement activation in combination with 20 minutes of hypoxia. Therefore, the autopsy findings in this series of trauma patients might represent the morphologic features of adult respiratory distress syndrome and multiple organ failure in an early, preclinical stage. ( Arch Surg 1988;123:1519-1524) |
| Databáze: | OpenAIRE |
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