Guillain-Barré syndrome incidence in a large United States cohort (2000-2009)
| Autor: | Irene M, Shui, Melisa D, Rett, Eric, Weintraub, Michael, Marcy, Anthony A, Amato, Sarah I, Sheikh, Doreen, Ho, Grace M, Lee, W Katherine, Yih, Lingling, Li |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Epidemiology Guillain-Barre Syndrome Cohort Studies symbols.namesake Age Distribution Sex Factors International Classification of Diseases medicine Humans Poisson regression Intensive care medicine Child Aged Aged 80 and over Guillain-Barre syndrome business.industry Medical record Incidence (epidemiology) Incidence Age Factors Infant Newborn Infant Emergency department Middle Aged medicine.disease United States Child Preschool Cohort symbols Female Neurology (clinical) Seasons business Demography Cohort study |
| Zdroj: | Neuroepidemiology. 39(2) |
| ISSN: | 1423-0208 |
| Popis: | Background/Aim: We describe the incidence of Guillain-Barré syndrome (GBS) in a large United States cohort. Methods: Between 2000 and 2009, we identified visits with an ICD-9 code for GBS (357.0) from all persons with continuous enrollment for at least 1 year. The primary case definition was restricted to emergency department and inpatient visits. We calculated age-standardized rates and used multivariate Poisson regression to assess variation in rates by sex, age, season and year of diagnosis. We tabulated descriptive characteristics and the positive predictive value (PPV) for a subset of the visits with available medical record review. Results: 1,619 visits with the GBS ICD-9 code were identified from 50,290,898 person-years of observation. After considering the PPV (55%) for record-reviewed visits, the age-standardized incidence rate was approximately 1.72/100,000 person-years. The rate was 40% higher for males and increased by 50% for every 10-year increase in age. The rate was 15% higher in winter and spring compared with summer. Rates were higher in more recent years. Conclusions: GBS rates are higher in males and increase considerably with age. The potential reasons for differences in rates by season and the increased rates in more recent years should be further investigated. |
| Databáze: | OpenAIRE |
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