Risk factors for isolation of Streptococcus pneumoniae with decreased susceptibility to penicillin G from patients infected with human immunodeficiency virus
| Autor: | J. Frottier, Frédéric Barbut, Marie-Caroline Meyohas, J. L. Meynard, L. Blum, Christos Chouaid, O. Picard, Jean-Claude Petit, Marguerite Guiguet |
|---|---|
| Přispěvatelé: | Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-École Supérieure Chimie Physique Électronique de Lyon-Centre National de la Recherche Scientifique (CNRS), Epidémiologie des maladies infectieuses et modélisation (ESIM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), JL Meynard, Barbut F, L Blum, M Guiguet, C Chouaid, Meyohas MC, O Picard, Petit JC, Frottier J, Université de Lyon-Université de Lyon-École Supérieure de Chimie Physique Électronique de Lyon (CPE)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Annesi-Maesano, Isabella |
| Jazyk: | angličtina |
| Rok vydání: | 1996 |
| Předmět: |
Male
Antibiotics MESH: Penicillin G medicine.disease_cause 0302 clinical medicine Risk Factors MESH: Risk Factors 030212 general & internal medicine MESH: Pneumococcal Infections Sida 0303 health sciences MESH: Middle Aged biology MESH: AIDS-Related Opportunistic Infections Penicillin G Middle Aged 3. Good health Infectious Diseases Streptococcus pneumoniae Superinfection Female Viral disease MESH: Streptococcus pneumoniae medicine.drug Microbiology (medical) Adult medicine.drug_class Penicillin Resistance Pneumococcal Infections 03 medical and health sciences medicine Humans Risk factor Retrospective Studies MESH: Humans AIDS-Related Opportunistic Infections 030306 microbiology business.industry MESH: Adult MESH: Retrospective Studies biology.organism_classification medicine.disease MESH: Penicillin Resistance Virology MESH: Male Penicillin Pneumonia [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie Immunology [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business MESH: Female |
| Zdroj: | Clinical Infectious Diseases Clinical Infectious Diseases, Oxford University Press (OUP), 1996, 22 (3), pp.437-40 Clinical Infectious Diseases, 1996, 22 (3), pp.437-40 |
| ISSN: | 1058-4838 1537-6591 |
| Popis: | International audience; We conducted a retrospective study of all hospitalized human immunodeficiency virus (HIV)-infected patients from whom a strain of Streptococcus pneumoniae was isolated (n = 45) between January 1992 and September 1994, in order to determine the clinical manifestations and outcome of and risk factors for infection by S. pneumoniae with decreased susceptibility to penicillin G. Such strains were isolated from 14 patients (31%), of whom 8 had pneumonia, 2 had bronchial superinfection, 2 had sinusitis, and 2 were colonized. All infected patients made a clinical recovery regardless of the MIC of the isolate. Indexes of HIV disease stage (CD4+ cell count and p24 antigenemia), antiretroviral treatment, and hospital admission in the previous 3 months did not influence the susceptibility of the isolates. For HIV-infected patients, treatment with antibacterial agents--particularly trimethoprim-sulfamethoxazole--in the previous 3 months is associated with an increased risk for isolation of S. pneumoniae with decreased susceptibility to penicillin G (relative risk, 5.0; 95% confidence interval, 1.9-13.3). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|