Chronic widespread pain is associated with slower cognitive processing speed in middle-aged and older European men

Autor: Steven Boonen, Felipe F. Casanueva, Thang S. Han, Carly Moseley, Ilpo Huhtaniemi, J. D. Finn, G Bartfai, John McBeth, Neil Pendleton, Abdelouahid Tajar, Frederick C. W. Wu, David Lee, Aleksander Giwercman, Gianni Forti, Dirk Vanderschueren, Michael E. J. Lean, Terence W O'Neill, Margus Punab, Krzysztof Kula, Alan J. Silman, Daryl B. O'Connor
Rok vydání: 2010
Předmět:
Zdroj: Pain. 151:30-36
ISSN: 0304-3959
Popis: Evidence from clinic-based studies suggests that the fibromyalgia syndrome (FMS) is associated with impairment in cognitive function though the mechanism is unclear. The aim of this analysis was to determine whether there is a similar association between chronic widespread pain (CWP), a cardinal feature of FMS, and impaired cognition in a community setting. Men (n=3369, 40-79 years) were recruited from population registers in eight centres for participation in the European Male Ageing Study (EMAS). The subjects completed a pain questionnaire and pain manikin, with the presence of CWP defined using the American College of Rheumatology criteria. The cognitive functions measured were visuospatial-constructional ability and visual memory (Rey-Osterrieth Complex Figure [ROCF]); visual recognition (Camden Topographical Recognition Memory test [CTRM]); and psychomotor processing speed (Digit-Symbol Substitution test [DSST]). We restricted our analysis to those subjects reporting pain that satisfied the criteria for CWP and those who were pain free. Of these 1539 men [mean (SD) age 60 (11) years], 266 had CWP. All cognitive test scores declined cross-sectionally with age (P
Databáze: OpenAIRE