Genome flux and stasis in a five millennium transect of European prehistory
| Autor: | János Dani, Cristina Gamba, Michael Hofreiter, Matthew D. Teasdale, László Domboróczki, Thomas Higham, Eppie R. Jones, Ron Pinhasi, Ivett Kővári, Russell L. McLaughlin, Alasdair Whittle, Valeria Mattiangeli, Gloria Gonzalez-Fortes, Daniel G. Bradley, Alexandra Anders, Ildikó Pap, Pál Raczky |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
Archaeogenetics
Time Factors Genotype Steppe Socio-culturale General Physics and Astronomy Skin Pigmentation Context (language use) Biology engineering.material Genomic Instability White People Article General Biochemistry Genetics and Molecular Biology Prehistory 03 medical and health sciences 0302 clinical medicine ddc:570 Ethnicity Humans Bronze History Ancient Institut für Biochemie und Biologie 030304 developmental biology Population Density Genetics Principal Component Analysis 0303 health sciences geography Multidisciplinary geography.geographical_feature_category Genome Human Population size Homozygote Genomics Sequence Analysis DNA General Chemistry Archaeology Extern Europe Lactase persistence Genetics Population Phenotype Iron Age engineering 030217 neurology & neurosurgery 570 Biowissenschaften Biologie |
| Zdroj: | Nature Communications |
| DOI: | 10.25932/publishup-43799 |
| Popis: | The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from 13 Hungarian Neolithic, Copper, Bronze and Iron Age burials including two to high (similar to 22x) and seven to similar to 1x coverage, to investigate the impact of these on Europe's genetic landscape. These data suggest genomic shifts with the advent of the Neolithic, Bronze and Iron Ages, with interleaved periods of genome stability. The earliest Neolithic context genome shows a European hunter-gatherer genetic signature and a restricted ancestral population size, suggesting direct contact between cultures after the arrival of the first farmers into Europe. The latest, Iron Age, sample reveals an eastern genomic influence concordant with introduced Steppe burial rites. We observe transition towards lighter pigmentation and surprisingly, no Neolithic presence of lactase persistence. Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe; 1332 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|