Management of Pulmonary Hypertension due to Heart Failure with Preserved Ejection Fraction
| Autor: | Ryan J. Tedford, Megan M. Clarke, Manreet Kanwar, Raymond L. Benza, George Sokos, Claire Walter, Srinivas Murali, Richa Agarwal |
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| Rok vydání: | 2014 |
| Předmět: |
Nephrology
medicine.medical_specialty Hypertension Pulmonary Population Blood Pressure Internal medicine Internal Medicine medicine Animals Humans Pulmonary venous congestion education Intensive care medicine Heart Failure education.field_of_study business.industry Hemodynamics Stroke Volume medicine.disease Pulmonary hypertension Patient population Underlying disease Heart failure Practice Guidelines as Topic Cardiology business Heart failure with preserved ejection fraction |
| Zdroj: | Current Hypertension Reports. 16 |
| ISSN: | 1534-3111 1522-6417 |
| DOI: | 10.1007/s11906-014-0501-5 |
| Popis: | Heart failure with preserved ejection fraction (HFpEF) is a major cause of HF-related morbidity and mortality, with no medical therapy proven to modify the underlying disease process and result in improvements in survival. With long-standing pulmonary venous congestion, a majority of HFpEF patients develop pulmonary hypertension (PH). Elevated pulmonary pressures have been shown to be a major determinant of mortality in this population. Given the paucity of available disease-modifying therapies for HFpEF, there has been a considerable interest in evaluating new therapeutic options specifically targeting PH in this patient population. |
| Databáze: | OpenAIRE |
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