Gingival squamous cell carcinoma masquerading as necrotizing ulcerative periodontitis
| Autor: | Saif Khan, Abdul Ahad, Jaiti Uppal, Kafil Akhtar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Gingival Squamous Cell Carcinoma
Periodontitis squamous cell carcinoma Pathology medicine.medical_specialty business.industry periodontal disease Case Report medicine.disease Delayed diagnosis Metastasis gingiva Lesion lcsh:RK1-715 stomatognathic diseases stomatognathic system lcsh:Dentistry immunohistochemistry medicine Carcinoma Periodontics Immunohistochemistry medicine.symptom business Vimentin expression |
| Zdroj: | Journal of Indian Society of Periodontology, Vol 25, Iss 1, Pp 61-64 (2021) Journal of Indian Society of Periodontology |
| Popis: | Necrotizing ulcerative periodontitis (NUP) is a painful and debilitating condition seen mostly in an immunocompromised state. Although squamous cell carcinoma (SCC) on gingiva is not uncommon, its presentation as a benign necrotizing lesion on gingiva is rare. Such presentations may lead to delayed diagnosis and poor prognosis. This report describes a case of a 34-year-old male presenting clinically with NUP around mandibular posterior teeth. Clinical features were misleading, but the histological findings established the diagnosis of well-differentiated SCC. Immunohistochemistry also showed features of epithelial–mesenchymal transition with decreased expression of E-cadherin and increased vimentin expression showing local invasion and metastasis. The patient was referred to the oncology department for evaluation of possible metastasis and further management of carcinoma. |
| Databáze: | OpenAIRE |
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