The Diagnostic Dilemma of Sarcoidosis: A Case of Acute Hypercalcemia
| Autor: | Vani Mulkareddy, Soham Upadhye, Preeti Siddam, Varun Bhalla |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty endocrine system diseases Diagnostic dilemma 030204 cardiovascular system & hematology Laboratory abnormality Malignancy 03 medical and health sciences 0302 clinical medicine Biopsy Site Biopsy Internal Medicine medicine sarcoidosis Hyperparathyroidism medicine.diagnostic_test business.industry Endocrinology/Diabetes/Metabolism General Engineering acute hypercalcemia medicine.disease Dermatology noncaseating granuloma Sarcoidosis Presentation (obstetrics) business 030217 neurology & neurosurgery |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.10399 |
| Popis: | Hypercalcemia is a common clinical laboratory abnormality with a majority of cases attributed to malignancy or hyperparathyroidism. Although hypercalcemia is a common manifestation of sarcoidosis, it is rarely the initial presentation. Here we present a case of acute hypercalcemia in a 60-year-old gentleman, which was diagnosed as sarcoidosis following an elaborate workup, including radiological assessment and multiple organ biopsies. This case highlights the diagnostic dilemma of sarcoidosis due to varying clinical presentation that can mimic multiple conditions, including malignancy. Biopsy showing noncaseating granulomas is pathognomic of sarcoidosis. Due to its multisystemic and nonspecific presentation, selecting an appropriate biopsy site is key to diagnosis. |
| Databáze: | OpenAIRE |
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