Reliability of body-weight scalars on the assessment of propofol induction dose in obese patients
| Autor: | Amílcar Falcão, Patrício Soares-da-Silva, Humberto S Machado, Ana M. Araújo |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Adolescent Remifentanil 030226 pharmacology & pharmacy Body Mass Index 03 medical and health sciences Young Adult 0302 clinical medicine 030202 anesthesiology medicine Clinical endpoint Humans General anaesthesia Arterial Pressure Obesity Rocuronium Propofol Aged business.industry Body Weight Reproducibility of Results General Medicine Middle Aged Anesthesiology and Pain Medicine Blood pressure Cross-Sectional Studies Anesthesia Body Composition Female business Bioelectrical impedance analysis Body mass index Anesthetics Intravenous medicine.drug |
| Zdroj: | Acta anaesthesiologica Scandinavica. 62(4) |
| ISSN: | 1399-6576 |
| Popis: | BACKGROUND Obese patients require specific perioperative care when compared with non-obese patients. The present study aimed to analyse the ability of size descriptors to estimate propofol induction dose in class II and III obese patients. METHODS A cross-sectional study on adult patients with body mass index (BMI) equal to or greater than 35 kg/m2 and on adult patients with BMI lower than 35 kg/m2 was carried out. General anaesthesia was induced with remifentanil, propofol and rocuronium. Propofol infusion was started at 2000 mg/h until loss of consciousness. Bioelectrical impedance analysis and Brice modified interview was completed during pre- and post-operative evaluation, respectively. Measurements of propofol plasma concentration were performed using gas chromatography/ion trap-mass spectrometry. RESULTS Forty patients were enrolled in the study. The median values of fat free mass (FFM) in BMI |
| Databáze: | OpenAIRE |
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