Role of vitamin D deficiency in continued hyperparathyroidism following parathyroidectomy
| Autor: | Donald L. Bodenner, Carolyn Redman, Brendan C. Stack |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Parathyroidectomy
Adult Male medicine.medical_specialty Adenoma medicine.medical_treatment Gastroenterology vitamin D deficiency Internal medicine medicine Vitamin D and neurology Humans Vitamin D Calcium metabolism Hyperparathyroidism business.industry medicine.disease Hyperparathyroidism Primary Vitamin D Deficiency Surgery Otorhinolaryngology Parathyroid Hormone Etiology Female business Primary hyperparathyroidism |
| Zdroj: | Headneck. 31(9) |
| ISSN: | 1097-0347 |
| Popis: | Background The aim of this study was to investigate vitamin D deficiency as an etiology for patients with elevated parathormone (PTH) levels after parathyroidectomy. Methods Fifity-five patients were identified who had undergone parathyroidectomy between January 2003 and November 2006 with complete records that included measurements of preoperative and postoperative PTH, vitamin D, calcium, ionized calcium, and sestamibi localization results. Results Thirteen patients (24%) had elevated PTH at 1 week postoperatively. Sixty-two percent of these patients (N = 8, 15% overall) had vitamin D deficiency. Thirty-one percent (N = 4, 7% overall) had persistent biochemical evidence of primary hyperparathyroidism. Three of the 4 had a subsequent positive sestamibi parathyroid localization of an additional adenoma (5.5% series incidence of double adenomas). Conclusion Given the known prevalence of vitamin D deficiency, consideration should be given to preoperative vitamin D testing to avoid confusion about the etiology of persistently elevated PTH following surgery. © 2009 Wiley Periodicals, Inc. Head Neck, 2009 |
| Databáze: | OpenAIRE |
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