Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor-positive desmoid tumor

Autor:	L. Copel, Judith Sandbank, Zvi Halpern, I. Samuk, Ariel Halevy, Yehiel Ziv
Rok vydání:	2006
Předmět:	Drug Adult Male medicine.medical_specialty media_common.quotation_subject Vinblastine Fatal Outcome Imaging Three-Dimensional Internal medicine Progesterone receptor medicine Tumor regression Humans Peritoneal Neoplasms media_common Medical treatment business.industry Anastomosis Surgical Proctocolectomy Restorative Gastroenterology Mifepristone Progesterone Receptor Positive Fibromatosis Aggressive Endocrinology Adenomatous Polyposis Coli Cancer research Disease Progression Surgery Drug Therapy Combination business Receptors Progesterone Tomography X-Ray Computed Estrogen receptor alpha medicine.drug
Zdroj:	Techniques in coloproctology. 14(3)
ISSN:	1128-045X
Popis:	We report the case of a patient who developed a desmoid tumor following total proctocolectomy and J-pouch reconstruction that was unresponsive to any medical treatment. Based on estrogen receptor alpha (ERalpha) and progesterone receptor (PR) evaluation (ERalpha-negative, but PR-positive), treatment with mifepristone, a pure antiprogesterone drug, was initiated, and partial tumor regression was achieved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a40f618ff96cb05aad77775f76b50f https://pubmed.ncbi.nlm.nih.gov/20585823 Zobrazit plný text záznamu Full text from SpringerLink