Comparison of Incidence of Myocardial Infarction in Patients With Rheumatoid Arthritis and Diabetes Mellitus
| Autor: | Dilpat Kumar, Amber Rizwan, Azka Ali, Maha Jahangir, Kanwal Elahi, Fnu Suman, Payal Tharwani, Ravi Kumar, Akhtar Ali, Zauraiz Anjum |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
education.field_of_study diabetes business.industry Incidence (epidemiology) Population Cardiology Endocrinology/Diabetes/Metabolism association General Engineering medicine.disease risk factor Internal medicine Rheumatoid arthritis Diabetes mellitus rheumatoid arthriitis Internal Medicine medicine Myocardial infarction Risk factor education business Prospective cohort study major adverse cardiovascular event Mace |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.15716 |
| Popis: | Introduction Patients with rheumatoid arthritis (RA) have a higher risk of cardiovascular diseases (CVDs) when compared to the general population, with most deaths attributed to myocardial infarctions (MI). However, patients with RA do not get the same attention in terms of cardiovascular screening as compared to other diseases, like diabetes mellitus (DM). Therefore, this study aims to compare the risk of CVD among patients with RA and DM. Methods This prospective study was carried out in Pakistan's two tertiary care hospitals. A total of 750 participants were enrolled in three groups with a 1:1:1 ratio; patients with RA, type 2 DM, and the control group. Patients were observed for 12 months or until the development of a major adverse cardiovascular event (MACE), whichever occurred first. Results Both fatal (12.66% vs. 13.48%; p-value: 0.79) and non-fatal (3.93% vs. 4.35%; p-value: 0.82) MI was comparable between both RA and DM group. However, compared to the control group, non-fatal MI (12.66% vs. 5.58%; p-value: 0.01) was significantly higher in the RA group. Conclusion Our study shows that RA and DM have an equal risk of cardiovascular (CV) events. It is important that RA should be considered as a prominent risk factor for CV events. The management of these patients should be multidisciplinary, including cardiologists. |
| Databáze: | OpenAIRE |
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