Beneficial effects of curcumin on antitumor activity and adverse reactions of doxorubicin
| Autor: | Yasuyuki Sadzuka, Yuko Ibuki, Takashi Sonobe, Tatsushi Toyooka, Makiko Nagamine |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Curcumin Cell Survival Pharmaceutical Science Antineoplastic Agents Apoptosis Pharmacology Lipid peroxidation chemistry.chemical_compound Mice Therapeutic index Cell Line Tumor polycyclic compounds medicine Animals Doxorubicin Viability assay Caspase Ovarian Neoplasms biology Chemistry technology industry and agriculture Cancer Sarcoma medicine.disease carbohydrates (lipids) Mice Inbred C57BL Caspases biology.protein Drug Therapy Combination Female Lipid Peroxidation Neoplasm Transplantation medicine.drug |
| Zdroj: | International journal of pharmaceutics. 432(1-2) |
| ISSN: | 1873-3476 |
| Popis: | Many medicines used in cancer chemotherapy decrease the quality of life (QOL). It is believed that an increase in food intake during cancer chemotherapy may produce an improvement in QOL. Curcumin is widely used as a coloring and flavoring agent in food. The effects of curcumin in relation to the chemotherapeutic drug doxorubicin (DOX) were examined. While DOX alone did not decrease tumor weight, the combination of DOX and curcumin significantly reduced tumor weight to 56.5% (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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