Supplementary Tables S1-S3 from Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors

Autor: Primo N. Lara, Chong-Xian Pan, David R. Gandara, Thomas Semrad, I-Yeh Gong, Karen Kelly, Mrinal P. Dutia, Tianhong Li, Nichole Mahaffey, Taiwo Akande, Monica Diaz, John S. Bomalaski, James A. Thomson, Benjamin K. Tomlinson
Rok vydání: 2023
DOI: 10.1158/1078-0432.22458221.v1
Popis: Supplementary Tables S1-S3. Table S1: The complete dose escalation schema for ADI-PEG 20 in combination with docetaxel. Table S2: Details the completed pharmacodynamic data for individual patients. Includes concentrations of arginine and citrulline over time and the titers of antibodies to ADI-PEG 20. Table S3: Highlights response against tumor type in patients where response was able to be assessed.
Databáze: OpenAIRE