Brain encoding of acupuncture sensation — Coupling on-line rating with fMRI
Autor: | Norman W. Kettner, Lauren LaCount, Mark Vangel, Richard E. Harris, Jieun Kim, Kyungmo Park, Rupali P. Dhond, Vitaly Napadow |
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Rok vydání: | 2009 |
Předmět: |
Adult
Male Cognitive Neuroscience Acupuncture Therapy Sensation Precuneus Pain Stimulation Brain mapping Article Young Adult Image Processing Computer-Assisted medicine Acupuncture Humans Skin Brain Mapping Brain Cognition Magnetic Resonance Imaging medicine.anatomical_structure Neurology Posterior cingulate Female Psychology Insula Neuroscience |
Zdroj: | NeuroImage. 47:1055-1065 |
ISSN: | 1053-8119 |
DOI: | 10.1016/j.neuroimage.2009.05.079 |
Popis: | Acupuncture-induced sensations have historically been associated with clinical efficacy. These sensations are atypical, arising from sub-dermal receptors, and their neural encoding is not well known. In this fMRI study, subjects were stimulated at acupoint PC-6, while rating sensation with a custom-built, MR-compatible potentiometer. Separate runs included real (ACUP) and sham (SHAM) acupuncture, the latter characterized by non-insertive, cutaneous stimulation. FMRI data analysis was guided by the on-line rating timeseries, thereby localizing brain correlates of acupuncture sensation. Sensation ratings correlated with stimulation more (p |
Databáze: | OpenAIRE |
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