Electrosynthesis of Phosphacycles via Dehydrogenative C–P Bond Formation Using DABCO as a Mediator

Autor:	Jun Yamashita, Eisuke Sato, Koichi Mitsudo, Seiji Suga, Yuji Kurimoto
Rok vydání:	2021
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Hydrogen atom DABCO Bond formation 010402 general chemistry Electrosynthesis Electrochemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound Mediator Physical and Theoretical Chemistry
Zdroj:	Organic Letters. 23:3120-3124
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.1c00807
Popis:	The first electrochemical synthesis of diarylphosphole oxides (DPOs) was achieved under mild conditions. The practical protocol employs commercially available and inexpensive DABCO as a hydrogen atom transfer (HAT) mediator, leading to various DPOs in moderate to good yields. This procedure can also be applied to the synthesis of six-membered phosphacycles, such as phenophosphazine derivatives. Mechanistic studies suggested that the reaction proceeds via an electro-generated phosphinyl radical.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6191f02e5ff9c684225dd56ee0cea8b1 https://doi.org/10.1021/acs.orglett.1c00807 Zobrazit plný text záznamu