Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices
| Autor: | T.J.A.G. Münker, S.E.C.M. van de Vijfeijken, C.S. Mulder, V. Vespasiano, A.G. Becking, C.J. Kleverlaan, L. Dubois, L.H.E. Karssemakers, D.M.J. Milstein, P.R.A.M. Depauw, F.W.A. Hoefnagels, W.P. Vandertop, T.J.J. Maal, E. Nout, M. Riool, S.A.J. Zaat |
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| Přispěvatelé: | ANS - Systems & Network Neuroscience, Graduate School, ACS - Microcirculation, Oral and Maxillofacial Surgery, Neurosurgery, Medical Microbiology and Infection Prevention, Dental Material Sciences, Maxillofacial Surgery (AMC), Laboratory Medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Materials science
Plasma Gases Biomedical Engineering 02 engineering and technology Biomaterials 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Fracture toughness Flexural strength Polymethyl Methacrylate Methyl methacrylate Composite material Precision Medicine Mechanical Phenomena Ethylene oxide Flexural modulus Sterilization Izod impact strength test 030206 dentistry Sterilization (microbiology) 021001 nanoscience & nanotechnology Poly(methyl methacrylate) Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] chemistry Mechanics of Materials Gamma Rays visual_art visual_art.visual_art_medium 0210 nano-technology |
| Zdroj: | Journal of the Mechanical Behavior of Biomedical Materials, 81, 168-172 Journal of the mechanical behavior of biomedical materials, 81, 168-172. Elsevier BV Journal of the Mechanical Behavior of Biomedical Materials, 81, 168-172. Elsevier BV CranioSafe Group 2018, ' Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices ', Journal of the Mechanical Behavior of Biomedical Materials, vol. 81, pp. 168-172 . https://doi.org/10.1016/j.jmbbm.2018.01.033 On behalf of the CranioSafe Group 2018, ' Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices ', Journal of the Mechanical Behavior of Biomedical Materials, vol. 81, pp. 168-172 . https://doi.org/10.1016/j.jmbbm.2018.01.033 Journal of the Mechanical Behavior of Biomedical Materials, 81, pp. 168-172 |
| ISSN: | 1878-0180 1751-6161 |
| DOI: | 10.1016/j.jmbbm.2018.01.033 |
| Popis: | BACKGROUND: Nowadays, personalized medical devices are frequently used for patients. Due to the manufacturing procedure sterilization is required. How different sterilization methods affect the mechanical behavior of these devices is largely unknown.MATERIALS AND METHODS: Three poly(methyl methacrylate) (PMMA) based materials (Vertex Self-Curing, Palacos R+G, and NextDent C&B MFH) were sterilized with different sterilization methods: ethylene oxide, hydrogen peroxide gas plasma, autoclavation, and γ-irradiation. Mechanical properties were determined by testing the flexural strength, flexural modulus, fracture toughness, and impact strength.RESULTS: The flexural strength of all materials was significantly higher after γ-irradiation compared to the control and other sterilization methods, as tested in a wet environment. NextDent C&B MFH showed the highest flexural and impact strength, Palacos R+G showed the highest maximum stress intensity factor and total fracture work.CONCLUSION: Autoclave sterilization is not suitable for the sterilization of PMMA-based materials. Ethylene oxide, hydrogen peroxide gas plasma, and γ-irradiation appear to be suitable techniques to sterilize PMMA-based personalized medical devices. |
| Databáze: | OpenAIRE |
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