Respiratory Syncytial Virus Neutralizing Activity in Nasal Secretions Following Natural Infection
| Autor: | John Mills, Robert H. Parrott, R M Chanock, Joseph A. Bellanti, Julita O. Arrobio, Hyun Wha Kim, Carl D. Brandt |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Immunodiffusion
biology Complement Fixation Tests Infant Respiratory tract disease General Biochemistry Genetics and Molecular Biology Virus Neutralization Serum antibody Respiratory Syncytial Viruses Nasal Mucosa medicine.anatomical_structure Rs virus Child Preschool Antibody Formation Immunology Methods medicine biology.protein Humans Respiratory system Antibody Respiratory Tract Infections Nose |
| Zdroj: | Experimental Biology and Medicine. 131:658-661 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-131-33946 |
| Popis: | SummaryThe development of RS virus neutralizing activity in nasal secretions was documented in 7 of 17 infants and children who were hospitalized for RS virus lower respiratory tract disease. Most of the patients in whom a rise in secretory neutralizing activity did not occur possessed moderately high levels of such activity in secretions collected at the time of admission to the hospital. At present we favor the view that this acute phase neutralizing activity represents antibody which developed early in the course of infection (possibly earlier than serum antibody) rather than the alternate possibility of nonspecific inhibitors in secretions. |
| Databáze: | OpenAIRE |
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