Early evaluation of severity in patients with severe sepsis: a comparison with 'septic shock' - subgroup analysis of the Japanese Association for Acute Medicine Sepsis Registry (JAAM-SR)
| Autor: | Shin-Ichiro Shiraishi, Yoshihiro Yamaguchi, Yasuo Miki, Joji Kotani, Takehiko Tarui, Ryosuke Tsuruta, Koichiro Suzuki, Shigeki Kushimoto, Naoki Aikawa, Hiroto Ikeda, Satoshi Gando, Seitaro Fujishima, Yasushi Suzuki, Kiyotsugu Takuma, Naoshi Takeyama, Toshihiko Mayumi, Norio Yamashita, Hiroshi Ogura |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Resuscitation Subgroup analysis Acute medicine Sepsis 03 medical and health sciences 0302 clinical medicine Internal medicine medicine In patient 030212 general & internal medicine Severe sepsis lactate business.industry Septic shock Mortality rate General Engineering 030208 emergency & critical care medicine Original Articles prediction medicine.disease mortality Surgery outcome Original Article Hypotension business |
| Zdroj: | Acute Medicine & Surgery |
| ISSN: | 2052-8817 |
| Popis: | Aim The purpose of this subgroup analysis of a Japanese multicenter registry, the Japanese Association for Acute Medicine Sepsis Registry Advanced (JAAM-SR-Advanced), was to identify early outcome indicators for severe sepsis that are useful and more objective than “septic shock.” Methods Among 624 patients with severe sepsis registered in JAAM-SR-Advanced, 554 with valid serum lactate data were retrospectively studied. Hypotension before and after fluid resuscitation and the highest lactate values over the initial 24 h were compared for their ability to predict in-hospital mortality. Results Of the study group, 155 (28.0%) patients were non-survivors and had significantly lower systolic blood pressures and higher lactate peaks. The mortality of 364 patients with initial hypotension was higher than those patients without it (32.7% versus 19.1%, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text