Prediction of functional reserves after lung resection: comparison between quantitative computed tomography, scintigraphy, and anatomy
| Autor: | James M Habicht, Claudius Gückel, Hermann Engel, André P. Perruchoud, Markus Solèr, Andreas Schoetzau, C Wyser, Michael Tamm, Chris T. Bolliger, Susanne Stöhr |
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| Rok vydání: | 2002 |
| Předmět: |
Pulmonary and Respiratory Medicine
Spirometry Male medicine.medical_treatment Vital Capacity Perfusion scanning Scintigraphy Pneumonectomy Oxygen Consumption Forced Expiratory Volume Medicine Humans Postoperative Period Prospective Studies Quantitative computed tomography Prospective cohort study Radionuclide Imaging Lung Aged medicine.diagnostic_test business.industry Middle Aged Respiratory Function Tests medicine.anatomical_structure Female Tomography business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | Respiration; international review of thoracic diseases. 69(6) |
| ISSN: | 0025-7931 |
| Popis: | Background and Objectives: We prospectively compared five techniques to estimate predicted postoperative function (ppo F) after lung resection: recently proposed quantitative CT scans (CT), perfusion scans (Q), and three anatomical formulae based on the number of segments (S), functional segments (FS), and subsegments (SS) to be removed. Methods: Four parameters were assessed: FEV1, FVC, DLCO and VO2max, measured preoperatively and 6 months postoperatively in 44 patients undergoing pulmonary resection, comparing their ppo value to the postoperatively measured value. Results: The correlations (r) obtained with the five methods were for CT: FEV1 = 0.91, FVC = 0.86, DLCO = 0.84, VO2max = 0.77; for Q: 0.92, 0.90, 0.85, 0.85; for S: 0.88, 0.86, 0.84, 0.75; for FS: 0.88, 0.85, 0.85, 0.75, and for SS: 0.88, 0.86, 0.85, 0.75, respectively. The mean difference between ppo values and postoperatively measured values was smallest for Q estimates and largest for anatomical estimates using S. Stratification of the extent of resection into lobectomy (n = 30) + wedge resections (n = 4) versus pneumonectomy (n = 10) resulted in persistently high correlations for Q and CT estimates, whereas all anatomical correlations were lower after pneumonectomy. Conclusions: We conclude that both Q- and CT-based predictions of postoperative cardiopulmonary function are useful irrespective of the extent of resection, but Q-based results were the most accurate. Anatomically based calculations of ppo F using FS or SS should be reserved for resections not exceeding one lobe. |
| Databáze: | OpenAIRE |
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