Usefulness of low iodine diet in managing patients with differentiated thyroid cancer - initial results
| Autor: | Drazen Huic, Marijan Zuvic, Margareta Dobrenic, Ratimir Petrovic, Tatjana Samardzic, Darko Grošev |
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| Rok vydání: | 2011 |
| Předmět: |
low iodine diet
urine iodine concentration medicine.medical_specialty medicine.medical_treatment differentiated thyroid cancer radioiodine chemistry.chemical_element Urine Iodine Gastroenterology Internal medicine medicine Radiology Nuclear Medicine and imaging Avidity In patient Thyroid cancer business.industry Thyroid medicine.disease Iodine deficiency medicine.anatomical_structure Oncology chemistry Thyroglobulin business Nuclear medicine Research Article |
| Zdroj: | Radiology and Oncology |
| ISSN: | 1581-3207 1318-2099 |
| DOI: | 10.2478/v10019-011-0017-4 |
| Popis: | Background. Low iodine diet (LID) is recommended in patients with differentiated thyroid cancer before radioiodine administration. Patients with increased thyroglobulin (Tg) level, but negative 131I whole body scan present diagnostic and therapeutic dilemma. This study was designed to evaluate the benefit of a two-week LID in patients with elevated serum Tg levels and negative 131I whole body scans. Patients and methods. For the impact assessment of two-week LID on radioiodine tissue avidity, radioiodine scans before and after LID were compared. Sixteen patients with serum Tg > 2 μg/L, negative Tg-antibodies, and negative radioiodine scans underwent two-week LID before the 131I administration. Fourteen patients underwent diagnostic scanning and two patients received radioiodine therapy. Iodine concentration in the morning urine specimens were measured in each patient, a day before and 15th day after starting LID. Results . Following self-managed LID, patients were able to significantly reduce their iodine body content by 50% (range 28-65%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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