External validation of ADNEX MR SCORING system: a single-centre retrospective study
| Autor: | Masanobu Mizuguchi, Kohei Sasaguri, Ken Yamaguchi, Masatoshi Yokoyama, Hiroyuki Irie, Shinichi Aishima, Takahiko Nakazono |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Scoring system Adolescent Malignancy Sensitivity and Specificity Severity of Illness Index 030218 nuclear medicine & medical imaging Diagnosis Differential Young Adult 03 medical and health sciences 0302 clinical medicine Adnexa Uteri medicine Humans Radiology Nuclear Medicine and imaging Child Aged Retrospective Studies Aged 80 and over Receiver operating characteristic medicine.diagnostic_test business.industry External validation Reproducibility of Results Magnetic resonance imaging Retrospective cohort study General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Single centre Adnexal Diseases 030220 oncology & carcinogenesis Female Radiology Ultrasonography business |
| Zdroj: | Clinical Radiology. 74:131-139 |
| ISSN: | 0009-9260 |
| DOI: | 10.1016/j.crad.2018.10.014 |
| Popis: | AIM To evaluate the accuracy of the ADNEX MR SCORING system for characterising adnexal masses. MATERIALS AND METHODS An institutional review board approved this retrospective study. The study population comprised 663 women who underwent magnetic resonance imaging (MRI) from January 2007 to December 2014 to characterise 778 adnexal masses that were indeterminate under ultrasonography (590 benign and 188 malignant). Two radiologists independently reviewed the MRI images. The masses were scored from 1 to 5 according to the ADNEX MR SCORING system. The diagnostic performance of the system was evaluated by receiver operating characteristic (ROC) analysis. Masses scored 4 or greater were considered malignant (including tumours of borderline malignancy or low malignant potential). RESULTS The malignancy rates of masses with scores of 2, 3, 4 and 5 were 1.9% (8/419), 12.8% (19/149), 62.6% (57/91) and 87.4% (104/119) for reader 1 and 2.1% (9/424), 13.6% (20/147), 67.6% (71/105) and 86.3% (88/102) for reader 2, respectively. The areas under the ROC curves for the differentiation of benign and malignant masses were 0.929 and 0.923, respectively; the sensitivity, specificity and accuracy of diagnosis were 85.6% (161/188), 91.7% (541/590), and 90.2% (702/778) for reader 1 and 84.6% (159/188), 91.9% (542/590), and 90.1% (701/778) for reader 2, respectively. Tumours of borderline malignancy or low malignant potential had a higher rate of misclassification (46.1%) than other malignant tumours (6–7.4%). CONCLUSION The ADNEX MR SCORING system was highly accurate in differentiating benign and malignant adnexal masses, although it may be less accurate for tumours of borderline malignancy or low malignant potential. |
| Databáze: | OpenAIRE |
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