Polymeric Nanoreactors as Emerging Nanoplatforms for Cancer Precise Nanomedicine
Autor: | Xikuang Yao, Xin Li, Fengwei Huo, Linhui Hao, Xiaopeng Zhao, Runkai Lv |
---|---|
Rok vydání: | 2021 |
Předmět: |
Materials science
Polymers and Plastics Polymers Static Electricity Cancer therapy Bioengineering Nanotechnology 02 engineering and technology Nanoreactor Cancer imaging 010402 general chemistry 01 natural sciences Theranostic Nanomedicine Biomaterials Mice Surface-Active Agents Bioreactors Neoplasms Materials Chemistry medicine Animals Humans Precision Medicine Electrostatic interaction Drug Carriers technology industry and agriculture Cancer Membranes Artificial Hydrogen-Ion Concentration 021001 nanoscience & nanotechnology medicine.disease Xenograft Model Antitumor Assays 0104 chemical sciences Nanostructures A549 Cells Imaging quality Solvents Nanomedicine 0210 nano-technology Biotechnology |
Zdroj: | Macromolecular bioscience. 21(6) |
ISSN: | 1616-5195 |
Popis: | How to precisely detect and effectively cure cancer which is defined as precise nanomedicine has drawn great attention worldwide. Polymeric nanoreactors which can in situ catalyze inert species into activated ones, can greatly increase imaging quality and enhance therapeutic effects along with decreased background interference and reduced serious side effects. After a brief introduction, the design and preparation of polymeric nanoreactors are discussed from the following aspects, that is, solvent-switch, pH-tuning, film rehydration, hard template, electrostatic interaction, and polymerization-induced self-assembly (PISA). Subsequently, the biomedical applications of these nanoreactors in the fields of cancer imaging, cancer therapy, and cancer theranostics are highlighted. The last but not least, conclusions and future perspectives about polymeric nanoreactors are given. It is believed that polymeric nanoreactors can bring a great opportunity for future fabrication and clinical translation of precise nanomedicine. |
Databáze: | OpenAIRE |
Externí odkaz: |