Neutralizing antibody titers to Omicron six months after vaccination with BNT162b2 in Colombia

Autor: María I. Zapata-Cardona, Lizdany Flórez-Álvarez, Tulio J. Lopera, Mateo Chvatal-Medina, Wildeman Zapata-Builes, Francisco J. Diaz, Wbeimar Aguilar-Jimenez, Natalia Taborda, Juan C. Hernandez, Maria T. Rugeles
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in immunology. 13
ISSN: 1664-3224
Popis: The emergence of the Omicron variant has generated concerns about the efficacy of COVID-19 vaccines. We evaluated the serum neutralizing activity of antibodies against the Omicron (lineage BA.1.1) by plaque reduction neutralizing test, as well as its correlation with age and gender, in a Colombian cohort six months after being vaccinated with BNT162b2 (Pfizer/BioNTech). Compared to all other variants analyzed, a significantly lower neutralizing activity (p
Databáze: OpenAIRE