Arterial rigidity as a marker of development of cardiovascular diseases in women having hypertensive disorders during pregnancy in anamnesis
| Autor: | I. V. Voevodina, Alina V Perederko, Olga S. Ivanova, S V Yureneva, Elena Yu Maychuk |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2019 |
| Předmět: |
Gestational hypertension
medicine.medical_specialty Aorta Pregnancy business.industry Obstetrics and Gynecology medicine.disease lcsh:Gynecology and obstetrics Blood pressure arterial stiffness Internal medicine medicine.artery medicine Cardiology Arterial stiffness gestational hypertension women business Body mass index Pulse wave velocity lcsh:RG1-991 Subclinical infection |
| Zdroj: | Гинекология, Vol 21, Iss 2, Pp 44-48 (2019) |
| ISSN: | 2079-5831 2079-5696 |
| Popis: | Currently, women-specific risk factors for cardiovascular diseases (CVD) are of particular importance, one of which is hypertensive disorders during pregnancy (HDP). The effect of hypertensive disorders on the formation of arterial stiffness as a predictor of CVD development remains insufficiently studied. Aim. To study the relationship of indicators of arterial stiffness, risk factors and metabolic changes with the presence of HDP in the history of women of different age groups. Materials and methods. The study included women aged 30 to 65 years, with one or more risk factors of CVD, which were divided into two groups: 1st - with preserved menstrual function and 2nd group - in the postmenopausal period with the presence or absence of HDP. All patients underwent daily blood pressure monitoring with determining the dynamics of central arterial pressure, determining the velocity of the pulse wave from the carotid to the femoral arteries, non-invasive determination of vascular stiffness indicators using the volume sphygmography method. Results. 90 women were examined. The first group consisted of 45 women (mean age 41±5.9 years); the second group - 45 women (mean age 55.3±5.8 years). In both groups, women with HDP are more likely to have burdened CVD heredity (p=0.02). In the 1st group with HDP, the average body weight and body mass index were significantly higher (p=0.02); menstrual disorders occurred more than twice as often (p=0.01) than in women without HDP. In the 2nd group with HDP abortions were more frequent (p=0.05) in history. In the 1st group with HDP, a significantly higher augmentation index AI (p=0.01); the average value of the average daily rate of the pulse wave in the aorta was also exceeded (11.7 m/s), which is 0.8 m/s higher than in women without HDP (p=0.02). Conclusion. A change in the AI and the average daily pulse wave velocity in the aorta, along with the presence of CVD risk factors and hormonal and metabolic disorders, are early markers of subclinical damage to target organs in women of reproductive age with a history of HDP. |
| Databáze: | OpenAIRE |
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