ESSPRI and other patient-reported indices in patients with primary Sjogren's syndrome during 100 consecutive outpatient visits at one rheumatological clinic
| Autor: | Markku Korpela, M. Pertovaara |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual Analog Scale Visual analogue scale Blood Sedimentation Ambulatory Care Facilities Severity of Illness Index Disease activity Disability Evaluation Rheumatology Surveys and Questionnaires Internal medicine medicine Humans Pharmacology (medical) In patient Finland Aged Retrospective Studies business.industry Beta-2 microglobulin Reproducibility of Results Middle Aged medicine.disease Peeling skin syndrome Sjogren's Syndrome Outpatient visits Physical therapy Female Self Report Sjogren s beta 2-Microglobulin business Biomarkers Rheumatism |
| Zdroj: | Rheumatology. 53:927-931 |
| ISSN: | 1462-0332 1462-0324 |
| DOI: | 10.1093/rheumatology/ket476 |
| Popis: | Objective. A European League Against Rheumatism (EULAR) SS disease activity index (ESSDAI) and a patient-reported index (ESSPRI) have recently been developed and validated. In our previous study the ESSDAI correlated significantly with serum b2 microglobulin concentration. We now aim to establish whether the ESSPRI is also associated with serum b2 microglobulin or with other patient-reported indices. Methods. The data on 100 consecutive visits of patients with primary SS (pSS) were reviewed from the patient charts. Patients who had filled out the ESSPRI questionnaire and fulfilled at least four of the revised AmericanEuropean consensus group criteria for pSS were included. Data were gathered on the ESSPRI (010 cm) and on the patient’s global health assessment [visual analogue scale (VAS) 010 cm] (PGH-VAS), pain-VAS (010 cm) and HAQ (range 03). Results. The ESSPRI correlated significantly with the PGH-VAS (r = 0.753, P < 0.0001), pain-VAS (r = 0.656, P < 0.0001) and HAQ (r = 0.542, P < 0.0001) (Spearman’s correlation). It also correlated weakly with serum b2 microglobulin (r = 0.214, P = 0.043) and ESR levels (r = 0.235, P = 0.019). Conclusion. The ESSPRI correlated significantly with other patient-reported indices, serum b2 microglobulin and ESR in patients with pSS. Our results support the view that the ESSPRI is a useful tool in the follow-up of patients with pSS. |
| Databáze: | OpenAIRE |
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