Assessment of Commercial Laboratories Performing Hair Mineral Analysis
| Autor: | Debra Gilliss, Sharon Seidel, Daniel Smith, Sandra V. McNeel, Richard Kreutzer |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Quality Control
business.industry Mineral analysis Sample (material) Reproducibility of Results Nutritional status General Medicine United States Trace Elements Qualitative analysis Split sample Metals Reference Values Environmental health Health care Healthy volunteers Humans Medicine Laboratories business Biomarkers Hair Split hair |
| Zdroj: | JAMA. 285:67 |
| ISSN: | 0098-7484 |
| DOI: | 10.1001/jama.285.1.67 |
| Popis: | ContextHair mineral analysis is being used by health care practitioners and promoted by laboratories as a clinical assessment tool and to identify toxic exposures, despite a 1985 study that found poor reliability for this test.ObjectiveTo assess whether the reliability of data from commercial laboratories advertising multimineral hair analyses for nutritional or toxicity assessment has improved since the 1985 study.Design, Setting, and ParticipantsA split hair sample taken from near the scalp of a single healthy volunteer was submitted for analysis to 6 commercial US laboratories, which analyze 90% of samples submitted for mineral analysis in the United States.Main Outcome MeasuresAgreement of test results for each analyte, laboratory reference ranges, laboratory characteristics, and interpretation of health implications.ResultsLaboratory differences in highest and lowest reported mineral concentrations for the split sample exceeded 10-fold for 12 minerals, and statistically significant (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|